PROSTATE SPECIFIC ANTIGEN

More than 60% of older males are affected with cancer of the prostate gland due to various reasons including environmental factors and pollution. There is a steady increase in the percentage of men prone to prostate cancer in the recent years. As the signs of disease are visible only at a later stage, more men are succumbed to prostate cancer. It has been found that men who take green tea regularly are less prone to prostate cancer than other men.

Oxidants are unstable molecules and are generally called free radicals. Oxidants rob electrons from other molecules in order to remain stable and during this process proteins and genetic materials are completely damaged. Antioxidant has the ability to scavenge the body and remove the unwanted toxins and waste materials. It also helps to seize oxidants and allow the repair to DNA that was damaged during the process.

Green tea is rich in antioxidants and polyphenols, having a cup of green tea twice a day reduces the risk of getting affected with prostate cancer by 50%. More over green tea has the ability to inhibit the growth of prostate cancer. In studies with mice affected with prostate cancer it has been found out, that the size of the tumor started to shrink after the mice were fed green tea for a period of one month. Also the green tea had the ability to fight against the cancer causing abnormal cells. By regularly drinking green tea and taking foods rich in antioxidants older men’s can help avoid the risk of getting infected with prostate cancer.

It has been found recently that nuclear stat5 over-expression could lead to the spread of prostate cancer to the other organs of the body. Stat proteins are found to be one of the key factors that could cause the development of oncogenesis. According to a latest research with mice it came to light that Stat5 is the primary reason to push the spreading of prostate cancer. Until now it was known that Stat5 was the reason for tumors but its role in spreading the cancer of prostate came to be known only recently. Stat5 (Signal Transduction and Transcription) proteins are the cause factor to alter the cell growth, differentiate it, and allow the abnormal cells to survive.

Stat5 is a protein that can regulate the expression of other genes and patients who were treated with prostate cancer were found to have prostate cancer again and this recurrence of prostate cancer was due to the active role of Stat5. Moreover patients with high amount of stat5 protein were more resistant to hormone therapy. Based upon a research in mice, prostate cancer was brought under control after stat5 was blocked completely and also there was no recurrence of prostate cancer.

The main cause for the prostate cancer cells to survive and multiply was Stat5 proteins. Rearrangement of the cytoskeleton of the prostate cancer cells also took place with the help of stat5. In addition this protein suppressed the binding of cells naturally and became a vital agent in abnormal development of cells. Mice which had over expression Stat5 were tested by injecting prostate cancer cells, readily the abnormal cells started to spread to vital organs like the liver, lungs, lymph nodes, bones and too many other organs. The findings with the mice also revealed that stat5 played an important role in the metastatic progression of human prostate cancer cells.

Prostate is a deadly killer disease that is increasing alarmingly all over the world; it can change the life style of a person completely. The treatments for prostate cancer resulted in unwanted side effects which made the patients suffer more, along with the deadly disease.

Males who were affected with prostate cancer could not hold back urine for a long time or pass urine without an uninterrupted flow. Moreover it affected the sex life of the victims, they could not maintain an erection nor could have a strong erection. As prostate cancer is a deadly disease, prevention is the best way to protect you. Regular screening of PSA can help you to rule out the disease at an early stage.

BPH is Benign Prostatic Hyperplasia or benign prostatic hypertrophy, it is a condition in which the prostate gland becomes enlarged in older males. BPH is non-cancerous growth and there is a rapid increase in the number of cells in the prostate gland. As a man grows older there are more chances of prostate gland to enlarge, a normal prostate gland grows throughout the lifetime of a man, but during the second phase of growth during the sixties there are more chances of enlargement of the prostate gland.

The cause factor for the enlargement of the gland was unknown for decades, recently based upon the studies conducted on animals showed that increase in amount of estrogen is a main factor that contributed to the growth of cells in the prostate gland. Men secrete large amount of testosterone and small amount of female hormone estrogen throughout the lifetime, but when they become old, the secretion of testosterone decreases and estrogen rises. The rise in female hormone is one of the main factors that lead to prostate enlargement or BPH.

With BPH urinary bladder in males will start to lose its function, emptying of the bladder will not take place completely. Few of the symptoms related with this disease are weak flow of urine, leaking and the need for frequent urination. In most males as the disease becomes worse and the victim may not be able to pass urine.

BPH symptoms can be relieved or lessened by employing various procedures. Transurethral microwave procedure is used in patients with enlarged prostate gland; it involves destroying the excess or unwanted tissues with the heat energy produced by the microwaves. This procedure requires less time and there is no need for the patient to get hospitalized. Other treatments include water induced thermotherapy, transurethral needle ablation and high intensity ultrasound. Although all of these procedures do not treat the disease itself, they are only symptomatic treatments and do not address the source of the disease.

Many prostate cancer victims undergo surgery to remove the tumor or cancerous growth, but the surgery can cause complications affecting the normal sexual activity of men. More than 80% of the men who undergo surgery suffer from erectile dysfunction. Men’s self esteem and quality of life will be affected due to erectile dysfunction. The nerve endings which enhance the erection are often damaged during the prostatectomy which results in erectile dysfunction.

Based upon recent research study, conducted on rats, regeneration of the nerves damaged during surgery can be assisted with the help of a protein. Sonic hedgehog is a protein that can speed up the healing process as well as help prevent the cellular damage in the penis which is necessary for maintaining a normal erection. Rats which were administered with Sonic hedgehog responded double time than the natural regeneration of cell on its own.

Erectile dysfunction caused by cavernous nerve damage needs great treatment to heal the damaged nerve. Sonic hedgehog may help damaged nerves and in addition, this protein activates the function of other proteins.

In recent years many men are diagnosed with prostate cancer at an early stage and as a result of the treatment their normal sex life is affected completely. The PSA ZERO program can help men avoid the invasive treatment procedures, nerve damage, and retain their erectile function while leading a normal sexual life.

Tasquinimod is an effective drug that can delay the progression of prostate cancer by blocking the blood vessels. Tumors generally require more amount of blood supply to provide nutrients to the tissues present in the tumor.By blocking new blood vessel development, the progression or development of prostate cancer can be avoided. Tasquinimod is an “anti-angiogenesis” drug which can “squeeze off’”the blood supply to the tumors and thereby causing it to starve.

Patients affected with prostate cancer where made to undergo a research and given a pill once a day for four months and when they were tested after six months of time 57% of patients who took Tasquinimod had no progression of prostate vs. the 33% of the patients who took the placebo.

Just like most of the drugs, Tasquinimod also has side effects that could adversely affect the human body. The patients who took Tasquinimod regularly had bone loss, fatigue, pain and stomach problems. Rarely few patients experienced deep vein thrombosis and stroke.

It’s always better to be on the safer side than to be sorry. If the proper treatment program, such as PSA ZERO, is administered at the right time prostate cancer patients can prolong their life as well as save themselves from the deadly disease.